منابع مشابه
Cyclodextrins Micronization by Supercritical Assisted Atomization
Supercritical Assisted Atomization (SAA) has been used to micronize α-cyclodextrin (α-CD) and hydroxypropyl-β-cyclodextrin (HP-β-CD). The effect of some process parameters such as precipitation temperature and solute concentration in the liquid solution has been studied to evaluate their influence on morphology and size of precipitated particles. Cyclodextrins micronization has been obtained wi...
متن کاملSupercritical Antisolvent Micronization of Minocycline Hydrochloride
Micronization of minocycline hydrochloride dissolved in ethanol and with supercritical carbon dioxide as antisolvent was successfully performed using a recently built SAS apparatus. Amorphous particles of minocycline ranging from 100 to 1000 nm (depending on the operating conditions) were obtained. The mean particle size and the particle size distribution were determined by Dynamic Light Scatte...
متن کاملEfavirenz Dissolution Enhancement I: Co-Micronization
AIDS constitutes one of the most serious infectious diseases, representing a major public health priority. Efavirenz (EFV), one of the most widely used drugs for this pathology, belongs to the Class II of the Biopharmaceutics Classification System for drugs with very poor water solubility. To improve EFV's dissolution profile, changes can be made to the physical properties of the drug that do n...
متن کاملPurification and Simultaneous Micronization of Polymers by Supercritical Antisolvent Precipitation
One of the most important environmental concerns for the polymer industry is to produce new products with near-zero residual monomer content. A new process based on supercritical CO2 has been successfully tested for the extraction of the residual monomer and the simultaneous micronization of the polymer. The process has been tested on a pilot-scale plant. The reduction of methyl methacrylate (M...
متن کاملEnhancement in Dissolution Rate of Piroxicam by Two Micronization Techniques
Piroxicam is a nonsteroidal anti-inflammatory drug that is practically insoluble in water. The oral absorption rate of piroxicam is dependent on its dissolution rate in the GI tract. The aim of this study was to enhance the dissolution of piroxicam by a microcrystallization technique. The preparation of microcrystals of piroxicam was done by two methods, solvent change and pH shift. In the solv...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Auto-Nomic Nervous System
سال: 1971
ISSN: 2185-9442,0387-0952
DOI: 10.3777/jjsam1948.18.5_99